Florence Comite Keynote Speaker

Founder, Comite Center for Precision Medicine & Health Longevity
Published researcher and bestselling author
Former Yale School of Medicine faculty member in Endocrinology and Reproductive Endocrinology, and founder of the nation's first women-only clinic

Florence Comite's Biography

Florence Comite, MD is a Yale- and National Institutes of Health-trained physician-scientist, a pioneering force in precision medicine, and a world-leading expert in longevity and endocrinology, renowned for her expertise in leveraging proprietary clinical and wearable data collected at her private clinical and virtual practice to detect, predict, and reverse biological aging and disorders of aging, and to optimize healthspan and vitality for life.

Data from her clinical research and decades of clinical practice informed Dr. Comite’s new book, Invincible: Defy Your Genetic Destiny to Live Better, Longer, an instant New York Times Bestselling book.

A graduate of Yale School of Medicine, where she was a faculty member for twenty-five years with a triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology), Dr. Comite trained at the National Institutes of Health and founded Women’s Health at Yale, the nation’s first women-only clinic.

In 2005, Dr. Comite founded the Comite Center for Precision Medicine & Health Longevity in New York City, where she established a clinically proven, academic approach to personalized healthcare structured around the individualized clinical process known as Nof1™, in which each patient is treated as a single-subject clinical trial. Her global clientele spans a broad population, from forward-thinking physicians to industry-disrupting executives and health-enthusiastic entrepreneurs. Each patient benefits from insights and interventions tailored specifically to their physiological make-up. In recent years, the Center has expanded to Palo Alto and Miami Beach.

Dr. Comite has published original research and articles in numerous clinical journals, such as the New England Journal of Medicine, JAMA: The Journal of the American Medical Association, and the Journal of the Endocrine Society. She is known for her seminal research in children, women, and men, grounded in the recognition that our entire biological system is critical to aging and disease. In 2013, she authored the bestselling book Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life, with a primary focus on androgen deficiency and vitality in aging men.

How to live to 120 (and Still Enjoy Living)

In this 45–60 minute keynote, Dr. Florence Comite draws on more than 30 years of clinical experience in longevity medicine to show audiences how to improve their healthspan—without spending hundreds of thousands of dollars or living a life of deprivation.

A pioneering physician-scientist, Dr. Comite has spent decades advancing precision medicine and proactive healthcare. She pioneered the N-of-1 approach long before personalized medicine became mainstream, published the first book on Precision Medicine and Healthspan in 2013, and has extensive clinical experience using biomarkers, peptides, GLP-1s, hormone optimization, metabolism, and Therapeutic Plasma Exchange.

At her private clinics in New York City, Miami, and Silicon Valley, Dr. Comite uses each patient's unique Health Story, biomarkers, and advanced diagnostics to identify chronic disease years before symptoms appear. An endocrinologist, she has never prescribed insulin, instead focusing on personalized interventions that help patients slow, prevent, or even reverse chronic disease.

Based on her New York Times bestselling book, Invincible: Defy Your Genetic Destiny to Live Better, Longer, Dr. Comite explains why longevity isn't about chasing perfection—it's about understanding your unique biology and making smarter decisions that lead to a healthier, more enjoyable life.

In this keynote, audiences will learn:

Why combining family health history with today's longevity technologies creates a more personalized approach to preventive care.
Why blood sugar management is central to healthy aging—and why sugar itself isn't the enemy.
The five essential biomarkers everyone should monitor and why "normal" isn't always optimal.
The facts and myths surrounding peptides and why Dr. Comite considers GLP-1s the "antibiotics of the 21st century."
How resistance training, quality sleep, personalized nutrition, and continuous health data work together to maximize healthspan.
Five practical habits anyone can begin today to improve long-term health and longevity.

Dr. Comite closes with a powerful reminder that the goal isn't simply to live longer—it's to live longer with the health, energy, and freedom to fully enjoy life.

Women Rising: Getting to 120 With Gayle, Oprah, and All the Other Queens

When Dr. Florence Comite appeared on CBS Mornings to discuss her instant New York Times bestselling book Invincible: Defy Your Genetic Destiny to Live Better Longer, Gayle King joked that if she was going to live to 120, Oprah would have to come too. It's a fitting reminder that longevity isn't a solo journey—our relationships help us build healthier habits and stay committed to them.

Drawing on more than 30 years of experience in precision medicine, Dr. Comite shares the lessons she's learned from founding Yale's first women's clinic and caring for executives, entrepreneurs, and leaders in New York, Silicon Valley, and Miami. She explains why women often prioritize everyone else's health before their own—and why investing in themselves is essential to living longer, healthier lives.

Addressing today's most talked-about longevity topics, including peptides, GLP-1s, hormone optimization, biomarkers, and precision medicine, Dr. Comite provides practical, evidence-based guidance tailored to the unique health challenges women face throughout every stage of life.

In this keynote, audiences will learn:

How hormone optimization can help women thrive through menopause and perimenopause.
Why testosterone plays an important role in women's health and longevity.
What women do well when managing their health—and where they can improve their long-term investment in themselves.
The five essential biomarkers every woman should understand and monitor.
Practical strategies for prioritizing sleep, nutrition, exercise, and recovery while balancing career, family, and caregiving responsibilities.
How understanding the Seven Disorders of Aging, genetics, and epigenetics can help women take a proactive approach to extending healthspan.

Dr. Comite inspires women to put their own health first so they can continue leading, giving, and making an impact for years to come.

Man Up: How to Close the Life Expectancy Gap and Feel Better, Longer

With more than 30 years of experience in longevity medicine, Dr. Florence Comite has helped redefine men's health through precision medicine. Her groundbreaking book, Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life!, pioneered the use of data to optimize metabolism, testosterone, and long-term health at the cellular level.

At her private clinics in New York City, Silicon Valley, and Miami Beach, Dr. Comite works with executives, entrepreneurs, and business leaders to address the unique health challenges men face as they age. In this practical keynote, she shares evidence-based strategies for extending healthspan, improving performance, and closing the life expectancy gap.

In this keynote, audiences will learn:

How andropause and periandropause affect men's health and performance.
Why midlife changes can be important indicators of long-term health.
What men do well when investing in their health—and where they can learn from women's approach to preventive care and family health history.
The five essential biomarkers every man should monitor to support healthy aging.
Practical strategies for prioritizing sleep, nutrition, exercise, and recovery while balancing career and family demands.
How understanding the Seven Disorders of Aging, genetics, and epigenetics can help identify future health risks and improve long-term outcomes.

Dr. Comite equips audiences with practical tools to take control of their health today so they can perform at a higher level, feel better longer, and enjoy a healthier future.